Caution About Overinterpretation of Number of Reflux Episodes in Reflux Monitoring for Refractory Gastroesophageal Reflux Disease

Refractory gastroesophageal reflux disease

Gastroesophageal reflux disease (GERD) is a condition that develops when the reflux of stomach contents into the esophagus causes troublesome symptoms, esophageal injury, and/or complications. Use of proton pump inhibitors (PPI) remains the standard therapy for GERD and is effective in most patients. Those whose symptoms are refractory to PPIs should be evaluated further and other treatment opt...

Refractory gastroesophageal reflux disease.

CONTEXT Gastroesophageal reflux disease (GERD) is a condition which develops when the reflux of stomach contents causes troublesome symptoms and/or complications. Its pathophysiology, diagnosis and treatment have frequently been analyzed but it is interesting to review some aspects of the GERD refractory patients to the proton pump inhibitors treatment. The treatment encompasses behavioral meas...

Refractory Gastroesophageal Reflux Disease – Evaluation and Management

Effect of Ramadan fasting on Gastroesophageal reflux disease symptoms

Background: Effect of Ramadan fasting on gastroesophageal reflux disease (GERD) is unknown and limited studies have been conducted in this regard. Nutritional, physiological, psychological and behavioral changes in fasting individuals during Ramadan may affect GERD. The present study aimed to evaluate the effects of these changes on GERD symptoms with more meticulous method. Materials and Metho...

Gastroesophageal Reflux Disease (GERD)

 Diagnosis History. If classic symptoms of heartburn and acid regurgitation dominate a patient’s history, then they can help establish the diagnosis of GERD with sufficiently high specificity, although sensitivity remains low compared to 24-hour pH monitoring. The presence of atypical symptoms (Table 1), although common, cannot sufficiently support the clinical diagnosis of GERD [B*]. Testing....